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Laboratory Planetary Ball Mill Grinder Crushing Machine
The Laboratory Mini Ball Mill Grinder Crushing Machine is a powerful tool designed for sample preparation in scientific research and industrial laboratories. The ball mill grinder operates on the principle of impact and friction, where the grinding jars and grinding balls create high-energy collisions that pulverize the sample into fine particles. This device is highly effective in reducing samples to micron or even nano-scale sizes, making it ideal for materials ranging from pharmaceuticals and biological samples to minerals and chemicals.
The instrument’s working mechanism involves the grinding jars rotating in the opposite direction to the sun wheel. This movement generates a high level of centrifugal force, which, in turn, causes the grinding balls to move with immense kinetic energy. As a result, the samples are subjected to repeated impacts and frictional forces against the inner walls of the grinding jar, leading to efficient and uniform particle size reduction. The laboratory ball mill is also equipped with advanced features, such as adjustable rotational speed, automated reverse rotation, and various material options for the grinding jars, ensuring flexibility and convenience for different research applications.
Advantages of the Laboratory Mini Ball Mill Grinder Crushing Machine
- Long-term sample preparation and continuous operation capability
- Adjustable rotational speed and stable operation for grinding to micron (dry grinding) and nano sizes (wet grinding)
- Automatic reverse rotation to prevent sample agglomeration
- Various grinding jar materials available, such as stainless steel, tungsten carbide, nylon, and more
- Advanced user interface for simple and convenient operation
Applications
The ball mill grinder is versatile and can be used in numerous fields:
- Pharmaceuticals and Herbal Medicines: Grinding of ginseng, tablets, medicaments, and more.
- Biological Samples: Efficient pulverization of plant materials, bones, and other biological specimens.
- Inorganic Materials: Preparation of samples like glass, iron powder, and ceramics for analysis.
- Organic Materials: Processing of substances like coke, coal, ink, and carbon fiber.
- Minerals: Crushing and homogenization of samples including iron ore, limestone, and quartz.
- Others: Suitable for materials like paper, polymers, pigments, catalysts, and more.
Technical Specifications
| Parameter | Details |
|---|---|
| Name | Planetary Ball Mill |
| Model | 4LQM-3SP4 |
| Operation Mode | Dial Button Type |
| Minimum Processing Volume | 50 ml/jar |
| Maximum Processing Volume | 4 x 1500 ml |
| Continuous Operation Time | 0-3600 min |
| Pause Time | 0-3600 s |
| Sun Wheel Speed | 35-335 r/min |
| Grinding Jar Speed | 70-670 r/min |
| Grinding Method | Dry Grinding/Wet Grinding |
| Low-Temperature Cooling | Optional |
| Inert Gas Protection | Yes |
| Net Weight | 92.8 kg |
| Dimensions | 770 x 500 x 580 mm |
Overall, the Laboratory Mini Ball Mill Grinder Crushing Machine offers a powerful, efficient, and flexible solution for a wide range of sample preparation needs in scientific and industrial laboratories. With its advanced features and adaptability, it is an essential tool for achieving precise and consistent results in various research fields.
About Our Factory
Established in 2008, our company has always been aiming at providing high quality laboratory homogenizers at competitive prices. We have a modern production workshop and warehouse of 5500 square meters, with an average daily production capacity of more than 300 units.
Our products include: Enhanced Multi-Sample Tissue Mill, Enhanced Fully Automated Sample, Enhanced Freeze Grinder, Multi-Sample Tissue Mill, Fully Automated Sample Rapid Grinder, Cryogenic Tissue Mill.
What We Do
As the world’s leading supplier of tissue mills, our factory is passionate about grinding technology. We offer a wide range of products including handheld tissue mills, frozen tissue grinders, high throughput tissue grinding machines, bead grinders, soil grinding machines, and other types of grinding equipment to our customers around the globe.
Our grinder products are widely used for grinding and breaking of various plant tissues, animal tissues, fungi and bacteria, plastics, polymers, food products, pharmaceutical tablets, hair, bones, chlorophyll A, soil and other samples.
Frequently Asked Question
Popular questions about soil grinding, hair grinding, plant tissue grinding and animal tissue grinding.
Tissue grinders are essential tools in laboratories for breaking down and homogenizing biological tissues to prepare them for further analysis. These devices are used to disrupt the cells within a sample, releasing their internal components like proteins, nucleic acids, and other biomolecules. This homogenization process is critical in various studies, including molecular biology, biochemistry, and histology, where precise tissue breakdown is required to extract cellular components or prepare tissues for further examination under a microscope. By creating a uniform suspension of tissue, grinders ensure consistent and reproducible results in experiments, which is crucial for maintaining the integrity and accuracy of scientific research.
In practice, tissue grinders are often used when researchers need to isolate specific cells or components, such as DNA, RNA, or enzymes, from a tissue sample. For example, in cancer research, tissue grinders can be employed to break down tumor tissues into a homogeneous solution to study cellular structures, gene expression, or protein function. Similarly, in pharmacological studies, they help in preparing tissue samples to assess the effects of various drugs at a cellular level. Thus, tissue grinders play a vital role in enabling a deeper understanding of biological processes and advancing various fields of scientific inquiry.
While both grinders and homogenizers are used in laboratories to process biological samples, they serve slightly different purposes and employ distinct mechanisms. A grinder is typically designed to physically break down larger pieces of tissue or plant material into smaller, more manageable fragments. This is often done through mechanical force, such as grinding or crushing with a pestle against a mortar, or using a blade to shear the tissue. Grinders are particularly useful when the goal is to create a coarse mixture or when working with relatively tough or fibrous materials that require significant mechanical disruption.
On the other hand, a homogenizer is used to achieve a much finer, uniform suspension or solution of cellular components. Homogenizers work by applying intense mechanical forces, such as high-pressure, rapid agitation, or ultrasonication, to thoroughly disrupt cell membranes and release intracellular contents into the surrounding medium. They are designed to create a consistent mixture where all components are evenly distributed, which is essential for applications like protein extraction, cell fractionation, or preparing samples for molecular analysis. In summary, while grinders are used for coarse breakdown of materials, homogenizers are designed to achieve a more thorough and uniform blending of the sample.
While both homogenizers and sonicators are used to break down and mix biological samples in the laboratory, they are not the same and operate on different principles. A homogenizer is a general term for any device that creates a uniform mixture by mechanically disrupting cells or tissues. This disruption can be achieved through various methods, such as high-pressure forces, bead beating, or mechanical stirring. The primary goal of a homogenizer is to ensure that all components within a sample are evenly distributed, making it suitable for applications like protein extraction, cell lysis, or preparing suspensions for analysis.
A sonicator, on the other hand, is a specific type of homogenizer that uses ultrasonic waves to achieve cell disruption and homogenization. It works by generating high-frequency sound waves that create microscopic bubbles in the liquid sample. These bubbles rapidly expand and collapse, a process known as cavitation, which generates intense mechanical forces that break apart cells and tissues. Sonicators are particularly useful for disrupting tough cell walls, like those found in bacteria or yeast, and for applications where a very fine level of homogenization is required.
In summary, while all sonicators are homogenizers, not all homogenizers are sonicators. Sonicators use ultrasonic energy to achieve homogenization, while other types of homogenizers may use different mechanical forces. The choice between a sonicator and another type of homogenizer depends on the specific requirements of the experiment, such as the type of sample, the level of cell disruption needed, and the desired consistency of the final mixture.
Homogenizing tissue for RNA extraction is a critical step to ensure the isolation of high-quality RNA, which is essential for various downstream applications like qPCR, RNA sequencing, and gene expression analysis. The goal of homogenization in this context is to break down the tissue structure and release the cellular RNA while minimizing degradation by RNases—enzymes that can quickly degrade RNA. To achieve this, the process must be carried out swiftly and under cold conditions to preserve RNA integrity.
To homogenize tissue for RNA extraction, start by placing the tissue sample in a cold, RNase-free container with a suitable lysis buffer, such as TRIzol or another guanidinium thiocyanate-based solution, which helps to denature proteins, inactivate RNases, and protect the RNA. Depending on the type of tissue, mechanical disruption can be performed using a homogenizer, such as a bead mill, rotor-stator homogenizer, or a mortar and pestle. Ensure that the homogenizer or beads are thoroughly cleaned and decontaminated to prevent RNase contamination. It’s essential to work quickly and keep the sample cold throughout the process to prevent RNA degradation.
Once homogenization is complete, you should have a uniform lysate free of visible tissue fragments. This lysate can then be further processed according to the RNA extraction protocol, typically involving steps like phase separation, RNA precipitation, washing, and resuspension. By thoroughly homogenizing the tissue and efficiently lysing the cells, you can maximize RNA yield and purity, leading to more reliable and accurate results in subsequent analyses.
Tissue homogenization is the process of mechanically breaking down tissue into a uniform mixture, or homogenate, to release cellular components such as proteins, DNA, RNA, and other biomolecules. This step is crucial in many biological and biochemical studies, as it allows researchers to obtain a consistent sample where all cells are evenly disrupted and their contents are accessible for further analysis. Homogenization can involve various methods, including mechanical grinding, bead beating, or ultrasonication, depending on the type and toughness of the tissue, as well as the specific requirements of the experiment.
The primary goal of tissue homogenization is to ensure that the sample is evenly processed, creating a solution where every part of the tissue has been broken down to the same extent. This uniformity is essential for obtaining reliable and reproducible results, whether isolating nucleic acids for genetic studies, extracting proteins for enzyme assays, or preparing samples for microscopy. The effectiveness of tissue homogenization also depends on the conditions under which it is performed, such as temperature and the choice of buffer, to prevent degradation of sensitive molecules like RNA or proteins.
By achieving a thorough and consistent breakdown of tissues, researchers can ensure that their samples are suitable for subsequent experimental steps. This foundational step in many laboratory workflows directly impacts the accuracy and reliability of downstream applications, such as gene expression analysis, protein quantification, or cell characterization.
A homogenizer is a key laboratory instrument used to break down and blend biological samples into a uniform mixture, or homogenate, to ensure consistent and efficient analysis. The primary purpose of a homogenizer is to disrupt cells, tissues, or other materials to release their internal contents—such as proteins, DNA, RNA, lipids, and other biomolecules—into a solution. This process is essential for experiments that require even distribution of these components, as it ensures that every part of the sample is equally represented, which is crucial for obtaining reliable and reproducible data.
Homogenizers are particularly valuable in applications such as molecular biology, microbiology, and pharmacology. For example, in molecular biology, a homogenizer might be used to extract RNA from tissue samples, ensuring that the RNA is released uniformly from all cells for accurate gene expression analysis. In microbiology, they can be used to break down bacterial or yeast cell walls to isolate intracellular contents for further study. In pharmacology, homogenizers help prepare tissue samples to test the effects of drugs at the cellular level. Overall, a homogenizer is vital for preparing samples in a wide range of scientific studies, enabling researchers to obtain the high-quality, homogeneous samples necessary for precise and effective research.
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You can customize any type of tissue grinder from our factory to meet your requirements.